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Shigeru Okada Selected Research

ferric nitrilotriacetate

7/2021The therapeutic potential of curcumin in alleviating N-diethylnitrosamine and iron nitrilotriacetate induced renal cell tumours in mice via inhibition of oxidative stress: Implications for cancer chemoprevention.
4/2009Curcumin attenuates oxidative damage in animals treated with a renal carcinogen, ferric nitrilotriacetate (Fe-NTA): implications for cancer prevention.
10/2007Probucol modulates iron nitrilotriacetate (Fe-NTA)-dependent renal carcinogenesis and hyperproliferative response: diminution of oxidative stress.
6/2005Suppressive effects of dietary curcumin on the increased activity of renal ornithine decarboxylase in mice treated with a renal carcinogen, ferric nitrilotriacetate.
1/2004Probucol as a potent inhibitor of oxygen radical-induced lipid peroxidation and DNA damage: in vitro studies.
10/2003Nitroglycerin, a nitric oxide generator attenuates ferric nitrilotriacetate-induced renal oxidative stress, hyperproliferative response and necrosis in ddY mice.
1/2003Differential role of hydrogen peroxide and organic hydroperoxides in augmenting ferric nitrilotriacetate (Fe-NTA)-mediated DNA damage: implications for carcinogenesis.
1/2003In vitro curcumin modulates ferric nitrilotriacetate (Fe-NTA) and hydrogen peroxide (H2O2)-induced peroxidation of microsomal membrane lipids and DNA damage.
8/2002Effects of phlebotomy on the growth of ferric nitrilotriacetate-induced renal cell carcinoma.

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Shigeru Okada Research Topics

Disease

13Neoplasms (Cancer)
07/2021 - 02/2002
12Carcinogenesis
04/2009 - 08/2002
7Necrosis
07/2017 - 01/2002
5Body Weight (Weight, Body)
07/2021 - 01/2002
5Type 2 Diabetes Mellitus (MODY)
07/2015 - 04/2007
5Inflammation (Inflammations)
01/2014 - 01/2004
4Fibrosis (Cirrhosis)
06/2010 - 12/2002
3Hypoxia (Hypoxemia)
06/2010 - 01/2007
3Renal Cell Carcinoma (Grawitz Tumor)
01/2004 - 08/2002
2Pulmonary Fibrosis (Fibrosing Alveolitis)
03/2017 - 01/2006
2Liver Diseases (Liver Disease)
10/2010 - 12/2002
2Hyperinsulinism (Hyperinsulinemia)
06/2010 - 04/2007
2Diabetes Complications
06/2010 - 01/2007
2Lung Injury
01/2007 - 01/2006
2Malaria
04/2005 - 10/2002
2Hepatocellular Carcinoma (Hepatoma)
12/2002 - 01/2000
1Melanoma (Melanoma, Malignant)
09/2019
1Lung Neoplasms (Lung Cancer)
07/2017
1Obesity
07/2015
1Weight Loss (Weight Reduction)
01/2014
1Insulin Resistance
01/2014
1Non-alcoholic Fatty Liver Disease
09/2013
1Pituitary Neoplasms (Pituitary Adenoma)
07/2011
1Acromegaly
02/2011
1Infections
08/2010
1Chronic Hepatitis C
08/2010
1Hepatitis C
08/2010
1Hemochromatosis (Bronze Diabetes)
06/2010
1Glucose Intolerance
06/2010
1Fatty Liver
11/2009
1Methemoglobinemia
11/2009
1Liver Cirrhosis (Hepatic Cirrhosis)
04/2009

Drug/Important Bio-Agent (IBA)

13Proteins (Proteins, Gene)FDA Link
07/2021 - 02/2002
9ferric nitrilotriacetateIBA
07/2021 - 08/2002
9IronIBA
06/2010 - 01/2000
7AntioxidantsIBA
09/2013 - 01/2003
5CurcuminIBA
07/2021 - 01/2003
4Pharmaceutical PreparationsIBA
09/2019 - 12/2003
4S-allylcysteine (allyl cysteine)IBA
03/2017 - 01/2006
4EnzymesIBA
04/2009 - 01/2003
3Insulin (Novolin)FDA Link
01/2014 - 03/2008
3Biomarkers (Surrogate Marker)IBA
01/2014 - 06/2010
3Protein Isoforms (Isoforms)IBA
01/2014 - 01/2007
3CarcinogensIBA
04/2009 - 02/2006
3Probucol (Lorelco)FDA Link
10/2007 - 12/2003
3CholesterolIBA
10/2007 - 12/2003
3Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
06/2005 - 01/2003
3Protective AgentsIBA
12/2003 - 01/2003
3Free RadicalsIBA
03/2003 - 08/2002
2Diethylnitrosamine (N-Nitrosodiethylamine)IBA
07/2021 - 10/2007
24-hydroxy-2-nonenal (4-hydroxynonenal)IBA
07/2021 - 04/2009
2CreatinineIBA
07/2017 - 01/2002
2Interleukin-6 (Interleukin 6)IBA
01/2014 - 01/2007
2Prealbumin (Transthyretin)IBA
01/2014 - 06/2010
2Chelating AgentsIBA
06/2010 - 12/2006
2Oxidants (Oxidizing Agents)IBA
10/2007 - 02/2006
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2007 - 08/2002
2Oxygen (Dioxygen)IBA
01/2007 - 01/2007
2Nitroglycerin (Dynamite)FDA LinkGeneric
03/2006 - 10/2003
2DNA (Deoxyribonucleic Acid)IBA
02/2006 - 01/2003
2Hemoglobins (Hemoglobin)IBA
04/2005 - 01/2000
2Hydroxyl RadicalIBA
01/2004 - 01/2003
18-Hydroxy-2'-DeoxyguanosineIBA
07/2021
1ATP-Binding Cassette Transporters (ABC Transporters)IBA
09/2019
1Transcription Factors (Transcription Factor)IBA
09/2019
1Growth Hormone (Somatotropin)IBA
09/2019
1Urea (Carbamide)FDA LinkGeneric
07/2017
1AsbestosIBA
07/2017
1NitrogenIBA
07/2017
1Carotenoids (Carotene)IBA
07/2017
1Bleomycin (Blenoxane)FDA LinkGeneric
03/2017
1Complement System Proteins (Complement)IBA
01/2014
1Nicotinamide PhosphoribosyltransferaseIBA
01/2014
1LipidsIBA
01/2014
1HaptoglobinsIBA
01/2014
1AdipokinesIBA
01/2014
1ClusterinIBA
01/2014
1Vitamin D-Binding ProteinIBA
01/2014
1Glucose (Dextrose)FDA LinkGeneric
09/2013
1yaku'amide AIBA
12/2010
1antioxidant biofactor AOBIBA
08/2010
1PPAR-betaIBA
06/2010
1Apolipoprotein A-I (Apolipoprotein A1)IBA
06/2010
1Kininogens (Kininogen)IBA
06/2010
1LigandsIBA
06/2010
1Blood Glucose (Blood Sugar)IBA
06/2010
1Blood Proteins (Serum Proteins)IBA
06/2010
1Transforming Growth Factor beta (TGF-beta)IBA
06/2010
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
06/2010
1Retinol-Binding Proteins (Retinoid Binding Proteins)IBA
06/2010
1Hydroxyproline (4 Hydroxyproline)IBA
12/2009
1NitritesIBA
11/2009
1Sodium NitriteIBA
11/2009

Therapy/Procedure

4Intraperitoneal Injections
07/2021 - 06/2003
3Therapeutics
09/2019 - 01/2004
2Chemoprevention
07/2021 - 01/2003
1Conservative Treatment
01/2014
1Tattooing
10/2010
1Body Piercing (Piercing, Body)
10/2010
1Oral Administration
12/2009